Obesity is a major health problem around the world. There are few effective treatments for obesity. For example, trying to change behavior has not resulted in weight loss, and other interventions, like medication and weight-loss surgeries such as gastric bypass, have serious side effects. Now there is a new option for treating obesity. A new study of a weekly shot of a drug called Semaglutide shows exciting results. In this study of 1,961 obese patients, Semaglutide was compared to a dummy placebo injection. Compared to the placebo injection, people taking Semaglutide had lost much more weight. For example, 86% of participants lost 5% or more of their body weight. However, there were concerns about side effects, such as nausea, vomiting, diarrhea and gallstones. It is important to note that most participants in this study were white and female, with only 12% Hispanic/Latino and 5% Black participants. Regardless, this is a good first step for people with obesity. Access to and the cost of this treatment are big considerations. At Sansum Diabetes Research Institute, we plan to be involved in a new study of Semaglutide pills for Hispanic/Latino adults with diabetes.