Prediabetes is a high risk state for diabetes. It is defined by blood sugar levels that are higher than normal, but still lower than the level to make a diagnosis of diabetes. Prediabetes is defined in many ways: high fasting blood glucose (100-125 mg/dL in America and 110-125 mg/dL elsewhere), or an impaired 2-hour glucose tolerance (140-199 mg/dL), or an elevated HbA1c level according to the American Diabetes Association (5.7%-6.4%) or International Expert Committee guidelines (6.0%-6.4%). Importantly, the amount of people with prediabetes is increasing around the world. According to the American Diabetes Association, up to 70% of individuals with prediabetes will eventually develop diabetes. In a recent review of the latest medical research (including 129 studies involving more than 10 million participants), new major findings were published. First, compared with people with normal blood sugar levels, prediabetes was linked to an increased risk of early death and cardiovascular disease in the general population and in patients who already had cardiovascular disease. Considering the high rates of prediabetes, successful intervention in this large population could have a major effect on public health. Although people with prediabetes commonly do not experience symptoms, prediabetes is a window of opportunity to prevent progression to type 2 diabetes and its complications.


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